Pigment International

REVIEW ARTICLE
Year
: 2020  |  Volume : 7  |  Issue : 1  |  Page : 12--25

Tranexamic acid in melasma: a review


Amrit Kaur1, Mala Bhalla1, Rashmi Sarkar2 
1 Department of Dermatology, Venereology and Leprosy, Government Medical College and Hospital, Chandigarh, India
2 Department of Dermatology, Venereology and Leprosy, MAMC, Delhi, India

Correspondence Address:
Dr. Mala Bhalla
Department of Dermatology, Venereology and Leprosy, Government Medical College and Hospital, Sector 32 B, Chandigarh, 160030
India

Tranexamic acid (TA), an anti-fibrinolytic agent, originally used for treating blood loss during surgery and various medical conditions, has been found to show promising results in melasma. TA has been tried as oral therapy, topical formulations and even intradermally, with or without adjuvants by various researchers in melasma but still there is no consensus on the optimum route, dose and timing of the treatment. A systematic literature search of the PubMed electronic database was performed using the keywords ‘melasma’, ‘chloasma’ and ‘tranexamic acid’ in the title. The abstracts of the articles were screened and reviewed for relevance. The selected articles were read in detail for inclusion and also the relevant references were traced. This review is an attempt to evaluate the role of TA by various routes in melasma and offer suggestions for future directions of research.


How to cite this article:
Kaur A, Bhalla M, Sarkar R. Tranexamic acid in melasma: a review.Pigment Int 2020;7:12-25


How to cite this URL:
Kaur A, Bhalla M, Sarkar R. Tranexamic acid in melasma: a review. Pigment Int [serial online] 2020 [cited 2020 Nov 25 ];7:12-25
Available from: https://www.pigmentinternational.com/article.asp?issn=2349-5847;year=2020;volume=7;issue=1;spage=12;epage=25;aulast=Kaur;type=0