| THE CLINICAL PICTURE |
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| Year : 2020 | Volume
: 7
| Issue : 1 | Page : 61-62 |
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Rain drop pigmentation in chronic arsenic poisoning
Anupam Das1, Anand Toshniwal2, Kunal Majumdar3
1 Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India
2 Aesthetic Aura Skin & Hair Clinic, Hyderabad, Telangana, India
3 Department of Community Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India
Correspondence Address:
Dr. Anupam Das
Building “PRERANA”, 19, Phoolbagan, Kolkata 700086, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/Pigmentinternational.Pigmentinternational_
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Contamination of ground water with arsenic is a problem being faced by over 30 countries in the world, since a few decades. Arsenicosis is a multisystem disorder characterised by cutaneous, gastrointestinal, urological and hematological manifestations. The WHO defines arsenicosis as a chronic health condition arising from prolonged ingestion (not less than 6 months) of arsenic above a safe dose, usually manifested by characteristic skin lesions, with or without involvement of internal organs. The WHO guideline for arsenic in drinking water is 0.01mg/ml. Cutaneous lesions are the earliest manifestations characterised by mottled pigmentation of covered areas of body called as rain drop pigmentation, blotchy mucosal pigmentation, depigmentation, palmoplantar pitting and keratosis.[1] Cutaneous malignancies which can be caused by arsenicosis include bowens disease, squamous cell carcinoma, basal cell carcinoma and melanoma.[2] It can also cause ischemic heart disease, hepatosplenomegaly, black foot disease and internal malignancies. [3]
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