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THE CLINICAL PICTURE
Year : 2020  |  Volume : 7  |  Issue : 1  |  Page : 61-62

Rain drop pigmentation in chronic arsenic poisoning


1 Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India
2 Aesthetic Aura Skin & Hair Clinic, Hyderabad, Telangana, India
3 Department of Community Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India

Correspondence Address:
Dr. Anupam Das
Building “PRERANA”, 19, Phoolbagan, Kolkata 700086, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/Pigmentinternational.Pigmentinternational_

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Contamination of ground water with arsenic is a problem being faced by over 30 countries in the world, since a few decades. Arsenicosis is a multisystem disorder characterised by cutaneous, gastrointestinal, urological and hematological manifestations. The WHO defines arsenicosis as a chronic health condition arising from prolonged ingestion (not less than 6 months) of arsenic above a safe dose, usually manifested by characteristic skin lesions, with or without involvement of internal organs. The WHO guideline for arsenic in drinking water is 0.01mg/ml. Cutaneous lesions are the earliest manifestations characterised by mottled pigmentation of covered areas of body called as rain drop pigmentation, blotchy mucosal pigmentation, depigmentation, palmoplantar pitting and keratosis.[1] Cutaneous malignancies which can be caused by arsenicosis include bowens disease, squamous cell carcinoma, basal cell carcinoma and melanoma.[2] It can also cause ischemic heart disease, hepatosplenomegaly, black foot disease and internal malignancies. [3]


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