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CASE REPORT
Year : 2016  |  Volume : 3  |  Issue : 2  |  Page : 108-110

Dyschromatosis universalis hereditaria in three siblings


Postgraduate Department of Dermatology, STD and Leprosy, Government Medical College, Srinagar, University of Kashmir, Jammu Kashmir, India

Correspondence Address:
Dr. Y J Bhat
Assistant Professor, Postgraduate Department of Dermatology, STD and Leprosy, Government Medical College, Srinagar, University of Kashmir, Jammu and Kashmir 190010
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2349-5847.196303

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Dyschromatosis universalis hereditaria (DUH) is a rare genodermatosis, which has been reported most often from Japan. The etiology of this disorder is not yet known. DUH is characterized by mixtures of hyperpigmented- and hypopigmented macules all over the body. Skin lesions are usually present in the first years of life. The trunk and extremities are the dominant sites. We report this pigmentary disorder in three siblings, two females and one male. These siblings presented with hypo- and hyperpigmented macules arranged in a reticulate pattern over trunk, dorsal and ventral aspects of legs and arms, and dorsa of both hands and feet. The biopsy findings were also consistent with DUH. Autosomal dominant pattern of inheritance was seen as one of the parents was also affected. There was no systemic involvement.


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