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REVIEW ARTICLE
Year : 2014  |  Volume : 1  |  Issue : 2  |  Page : 44-51

Physiologic pigmentation: Molecular mechanisms and clinical diversity


1 Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
2 Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Correspondence Address:
Neelam A Vashi
Department of Dermatology, 609 Albany Street J602, Boston, MA 02118
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2349-5847.147039

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Dyschromia is one of the leading diagnoses in skin of color of populations. Inclusive within this broad realm of diagnoses includes physiologic pigmentation, which refers to normal biologic variations in skin coloration. In order to properly diagnose and manage disorders of pigmentation, one must be aware of the normal variations in skin pigmentation. Our review summarizes molecular mechanisms and the diverse patterns of physiologic pigmentation that may be encountered in the clinic and that are especially common in richly pigmented individuals.


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